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Eisenmenger's syndrome or Eisenmenger's reaction is defined as the process in which a left-to-right shunt in the heart causes increased flow through the pulmonary vasculature, causing pulmonary hypertension, which in turn, causes increased pressures in the right side of the heart and reversal of the shunt into a right-to-left shunt.
Etymology
Eisenmenger's syndrome is named by Dr. Paul Wood after Dr. Victor Eisenmenger, who first described the condition in 18971. Eisenmenger V. Die angeborenen Defekte der Kammerscheidewände des Herzens.
Zeitschr Klin Med 1897;32(Supplement):1-28.
Etiology
A number of congenital heart defects can cause Eisenmenger's syndrome, including atrial septal defects, ventricular septal defects, patent ductus arteriosus, and more complex types of acyanotic heart disease.
References
- Wood, P. Pulmonary hypertension with special reference to the vasoconstrictive factor. Br Heart J 1958;20:557-570.
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